Hi there!
Not sure if your friend has done any of this with the exception of "reboot," but worth a try. May want to try these in order and proceed to the next step if it does not work.
Has your friend tried to quit those apps yet? To do this have her press the home button twice to see the bar of apps on the bottom of the screen. Find the apps that are not responding and long press onto the app until it shakes. When it starts to shake, touch the red negative sign in the corner of the app. This will not delete, but will close the app. Than open and retry to see if it works.
If not, than restart the ipad. Press the power switch until you get the slide lock to power off. Turn back on and retry.
If not, than reset the ipad. Press the power switch and the home button until the screen turns off. May take a few seconds to power off.
Give those a try and see if it helps her. Good luck and let us know.