Musclenerd has already tweeted that this point release is safe for jailbreakers, supporting DFU, saved SHSH Blobs, and synchronising of data as expected.
It your the type that likes to upgrade, fill yer boots!
To be honest I think it was back in the 3.1 (before iPad) days that an iTunes update last broke a jailbreak, but the pain is still remebered by some
Always best to check!