Hi. Thought I would tell you something that would be helpful regarding the common problem of Itunes connection timing out when attempting to download a current iPad update. I had this problem and tried every single suggestion I could find on the Internet. Nothing worked! I found a site that explained how to "Manually Update" by going directly to the Apple download site and downloading it and then following the manual directions. (This is the site entitled "How to Manually Update iPad." I'm not allowed to list the link since I'm new to this forum, but you can do an independent search. Even though the article specifically mentions IOS 4.3.3, I was able to find 4.3.5. HOWEVER, I still had the connection timeout message after a long time of it trying!
Since the problem seemed to be within my own computer; some kind of glitch or language, I decided it was also preventing my downloading directly from Apple as well and wasn't just an iTunes software problem. So, fortunately, I have an old 2002 XP desktop that I kept around because of the scanner I have. It never had Itunes loaded on it. I went to the website I listed above on how to download manually since it has the actual links and chose the link for my own Ipad 2 Wifi only. I started the download and it was downloading correctly! I happened to have Opera Browser on the computer since my XP is still SP1, so Internet Explorer won't work. Opera downloaded the file with the correct extension instead of creating a zip. I don't know if that matters, but at least I knew it was going correctly. Since I have DSL "Light" which is a speed much faster than dialup, but slower than high-speed broadband or DSL, it took about 8 hours. I made sure my desktop Power settings in the control panel were set to never turn off, but let my monitor sleep and went to bed.
The next morning, the file was downloaded and I was able to transfer it to a flash drive and put the file on my laptop that has itunes. (Make sure your flash drive is large enough since it is a 690 MG file!) I then followed the directions which are:
Connect the iPad to the computer with iTunes.
Open iTunes and let it find the iPad.
Back up the iPad if you haven''t done so recently.
Hold down the Shift Key and press the Update button.
A window will pop up letting you go through your folders and click on the update file.
It then goes through its process.
It was successful! In my particular circumstance and possibly the same as some of you; the key here was to download the file on a computer that never has had iTunes so that there is no corrupt file that is causing the problem of not connecting for downloading the update.
I hope this is helpful. I spent 3 days trying everything else.
Good luck.