You won't be able to downgrade to 4.3.3 (please note the correct numbers) if, and ONLY if, Apple has stopped signing the 4.3.3.
If they are still signing it - no problem, just go back to it.
It's when they stop signing an iOS version that this comes into play. If you have to restore your device and Apple has stopped signing a jailbreakable version AND you don't have SHSH blobs (which you can't do on 3G/CDMA versions) - you can only restore to the Apple version.
Example1: You are on 4.3.3, jailbroken with a 3G/CDMA iPad (can't save SHSH blobs). Apple has released nothing. For some reason, you have to restore your iPad. When you restore it, the only firmware version available for you to run on your iPad will be 4.3.3. You are very happy and simply re-jailbreak your iPad using the latest comex jailbreak. Done.
Example2: You are on 4.3.3, jailbroken with a 3G/CDMA iPad (can't save SHSH blobs). Apple goes to 4.3.4 (which is not jailbroken). You sit tight. Then, for some reason, you have to restore your iPad. When you restore it, the only firmware version available for you to run on your iPad will be 4.3.4. Since you want to actually use your iPad, rather than look at it as a pretty paperweight, you have to put 4.3.4 on it. Then, it's back to waiting/hoping that someone can develop a jailbreak for that verison.
Yeah, it's clear as mud, but hopefully this'll help...
Marilyn