MobileMe, as others have mentioned will do all of this. It is a very small price to pay (especially if you buy it on Amazon)...aside from cal, contact, bookmark, etc syncing...you get "Find My iPad" (if we're talking about a 3G iPad...otherwise...not sure if it works).... if you were to ever lose your iPad, you can log in to your MobileMe account from any browser, and either remotely lock down your iPad, GPS locate it, and send a message to it, like "please call XXXXX at XXX-XXX-XXXX to return device"...its awesome, and totally worth the price!
Again, as someone else mentioned...Google Apps (the $50/year/user pay version of Google that acts like Exchange, and can keep everything in sync for you). I happen to use both on my iPad... The only reason I ever connect my iPad to iTunes it to change up my video/photo/music content, or whenever they will have software updates...otherwise...no need!!
Good luck... just got one for my wife as well...its great with both of us having them...